TitleComplete genome sequence and annotation of the Treponema pallidum subsp. pallidum Chicago strain.
Publication TypeJournal Article
Year of Publication2010
AuthorsGiacani, L, Jeffrey, BM, Molini, BJ, Le, HVT, Lukehart, SA, Centurion-Lara, A, Rockey, DD
JournalJ Bacteriol
Date Published2010 May
KeywordsGenome, Bacterial, Molecular Sequence Data, Treponema pallidum

In syphilis research, the Nichols strain of Treponema pallidum, isolated in 1912, has been the most widely studied. Recently, important differences among T. pallidum strains emerged; therefore, we sequenced and annotated the Chicago strain genome to facilitate and encourage the use of this strain in studying the pathogenesis of syphilis.

Alternate JournalJ Bacteriol
PubMed ID20348263
PubMed Central IDPMC2863575
Grant ListR01 AI042143 / AI / NIAID NIH HHS / United States
R01 AI063940 / AI / NIAID NIH HHS / United States
AI42143 / AI / NIAID NIH HHS / United States
AI63940 / AI / NIAID NIH HHS / United States