| Title | Effect of acepromazine, diazepam, fentanyl-droperidol, and oxymorphone on gastroesophageal sphincter pressure in healthy dogs. |
| Publication Type | Journal Article |
| Year of Publication | 1987 |
| Authors | Hall, JA, Magne, ML, Twedt, DC |
| Journal | Am J Vet Res |
| Volume | 48 |
| Issue | 4 |
| Pagination | 556-7 |
| Date Published | 1987 Apr |
| ISSN | 0002-9645 |
| Keywords | Acepromazine, Analgesics, Opioid, Animals, Diazepam, Dogs, Droperidol, Drug Combinations, Esophagogastric Junction, Fentanyl, Oxymorphone, Pressure, Tranquilizing Agents |
| Abstract |
Treatment of healthy dogs with 4 commonly used psychotropic or analgesic agents significantly decreased resting gastroesophageal sphincter pressure (GESP). Acepromazine decreased GESP by 35% (P = 0.02); oxymorphone decreased GESP by 38% (P less than 0.005); diazepam decreased GESP by 42% (P = 0.005); and fentanyl-droperidol decreased GESP by 40% (P = 0.03). Therefore, esophageal manometric evaluation of gastroesophageal sphincter function should not be preceded by administration of these drugs.
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| Alternate Journal | Am J Vet Res |
| PubMed ID | 2884907 |
OREGON STATE UNIVERSITY
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