OREGON STATE UNIVERSITY
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| Title | LcrG is required for efficient translocation of Yersinia Yop effector proteins into eukaryotic cells. |
| Publication Type | Journal Article |
| Year of Publication | 1998 |
| Authors | Sarker, MR, Sory, MP, Boyd, AP, Iriarte, M, Cornelis, GR |
| Journal | Infection and immunity |
| Volume | 66 |
| Issue | 6 |
| Pagination | 2976-9 |
| Date Published | 1998 Jun |
| Keywords | Yersinia enterocolitica |
| Abstract | Extracellular Yersinia disables the immune system of its host by injecting effector Yop proteins into host cells. We show that a Yersinia enterocolitica nonpolar lcrG mutant is severely impaired in the translocation of YopE, YopH, YopM, YpkA/YopO, and YopP into eukaryotic cells. LcrG is thus required for efficient internalization of all the known Yop effectors. |