TitleA Method for Cross-Species Visualization and Analysis of RNA-Sequence Data.
Publication TypeJournal Article
Year of Publication2018
AuthorsRamsey, SA
JournalMethods Mol Biol
Date Published2018
KeywordsAlgorithms, Animals, Computational Biology, Computer Graphics, Dogs, Gene Expression Profiling, Humans, RNA, Messenger, Sequence Analysis, RNA, Urinary Bladder Neoplasms, Workflow

In this methods article, I describe a computational workflow for cross-species visualization and comparison of mRNA-seq transcriptome profiling data. The workflow is based on gene set variation analysis (GSVA) and is illustrated using commands in the R programming language. I provide a complete step-by-step procedure for the workflow using mRNA-seq data sets from dog and human bladder cancer as an example.

Alternate JournalMethods Mol Biol
PubMed ID29119511