OREGON STATE UNIVERSITY
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| Title | Mycobacterium avium uses apoptotic macrophages as tools for spreading. |
| Publication Type | Journal Article |
| Year of Publication | 2011 |
| Authors | Early, J, Fischer, KA, Bermudez, LE |
| Journal | Microbial pathogenesis |
| Volume | 50 |
| Issue | 2 |
| Pagination | 132-9 |
| Date Published | 2011 Feb |
| Keywords | Mycobacterium avium-intracellulare Infection |
| Abstract | Mycobacterium avium (MAC) lives and replicates in macrophages and causes disseminated disease in immunocompromised individuals. As a host response to control disease, many macrophages become apoptotic a few days after MAC infection. In this study, we hypothesized that MAC can survive autophagic and apoptotic macrophages and spread. |
| DOI | 10.1111/j.1365-3164.2011.00980.x |