TitleMyonecrosis in three horses with colic: evidence for endotoxic injury.
Publication TypeJournal Article
Year of Publication2007
AuthorsValentine, BA, Löhr, CV
JournalThe Veterinary record
Date Published2007 Dec 8
KeywordsSeptic, Shock

Three horses with colic, clinical evidence of endotoxaemia and high serum activities of creatine kinase and aspartate aminotransferase were examined postmortem. The horses were diagnosed with severe ulcerative colitis, pyloric ulceration and stenosis with colonic sand impaction, and colonic obstruction due to faecaliths. There was no gross or histological evidence of muscle trauma. Their semimembranosus muscles had scattered acute to subacute segmental necrosis of the myofibres, suggestive of endotoxin-induced muscle injury.