Title | Origins and functions of the chlamydial inclusion. |
Publication Type | Journal Article |
Year of Publication | 1997 |
Authors | Hackstadt, T, Fischer, ER, Scidmore, MA, Rockey, DD, Heinzen, RA |
Journal | Trends in microbiology |
Volume | 5 |
Issue | 7 |
Pagination | 288-93 |
Date Published | 1997 Jul |
Keywords | Biological, Models |
Abstract | Chlamydiae dissociate themselves from the endocytic pathway shortly after internalization by actively modifying the vacuole to become fusogenic with sphingomyelin-containing exocytic vesicles. Interaction with this secretory pathway appears to provide a pathogenic mechanism that allows chlamydiae to establish themselves in a site that is not destined to fuse with lysosomes.
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DOI | 10.1016/S0966-842X(97)01061-5 |