TitlePseudocapillaria tomentosa, a nematode pathogen, and associated neoplasms of zebrafish (Danio rerio) kept in research colonies.
Publication TypeJournal Article
Year of Publication2002
AuthorsKent, ML, Bishop-Stewart, JK, Matthews, JL, Spitsbergen, JM
JournalComp Med
Date Published2002 Aug
KeywordsAnimals, Animals, Laboratory, Female, Intestinal Neoplasms, Male, Nematoda, Nematode Infections, Zebrafish

Infections with capillarid nematodes were observed in zebrafish (Danio rerio) kept at several research facilities and in a large carcinogen exposure study previously conducted at Oregon State University. We report a morphologic description that identifies the worm as Pseudocapillaria tomentosa, a common nematode of cyprinid and other fishes. Pathologic lesions associated with the infection ranged from inflammatory changes to aggressive neoplasms of the intestine (i.e., intestinal carcinomas and mixed malignant neoplasms). Capillarid nematodes may have intermediate or paratenic hosts. Using a laboratory transmission study, we confirmed that the parasite has a direct life cycle.

Alternate JournalComp Med
PubMed ID12211280
Grant ListP40 RR12546 / RR / NCRR NIH HHS / United States