TitleStrategies to Mitigate a Mycobacterium marinum Outbreak in a Zebrafish Research Facility.
Publication TypeJournal Article
Year of Publication2016
AuthorsMason, T, Snell, K, Mittge, E, Melancon, E, Montgomery, R, McFadden, M, Camoriano, J, Kent, ML, Whipps, CM, Peirce, J
JournalZebrafish
Volume13 Suppl 1
PaginationS77-87
Date Published2016 07
ISSN1557-8542
KeywordsAnimal Husbandry, Animals, Aquaculture, Disease Outbreaks, Fish Diseases, Mycobacterium Infections, Nontuberculous, Mycobacterium marinum, Oregon, Zebrafish
Abstract

In 2011, the zebrafish research facility at the University of Oregon experienced an outbreak of Mycobacterium marinum that affected both research fish and facility staff. A thorough review of risks to personnel, the zebrafish veterinary care program, and zebrafish husbandry procedures at the research facility followed. In the years since 2011, changes have been implemented throughout the research facility to protect the personnel, the fish colony, and ultimately the continued success of the zebrafish model research program. In this study, we present the history of the outbreak, the changes we implemented, and recommendations to mitigate pathogen outbreaks in zebrafish research facilities.

DOI10.1089/zeb.2015.1218
Alternate JournalZebrafish
PubMed ID27351618
PubMed Central IDPMC4931754
Grant ListP01 HD022486 / HD / NICHD NIH HHS / United States
P50 GM098911 / GM / NIGMS NIH HHS / United States
R01 CA176579 / CA / NCI NIH HHS / United States
R24 OD010998 / OD / NIH HHS / United States