TitleA subinhibitory concentration of clarithromycin inhibits Mycobacterium avium biofilm formation.
Publication TypeJournal Article
Year of Publication2004
AuthorsCarter, G, Young, LS, Bermudez, LE
JournalAntimicrobial agents and chemotherapy
Volume48
Issue12
Pagination4907-10
Date Published2004 Dec
KeywordsQuinolines
Abstract

Mycobacterium avium causes disseminated infection in immunosuppressed individuals and lung infection in patients with chronic lung diseases. M. avium forms biofilm in the environment and possibly in human airways. Antibiotics with activity against the bacterium could inhibit biofilm formation. Clarithromycin inhibits biofilm formation but has no activity against established biofilm.

DOI10.1128/AAC.48.12.4907-4910.2004