Carlson College of Veterinary Medicine

L. E. Bermudez, Inderlied, C. B., Kolonoski, P., Chee, C. B., Aralar, P., Petrofsky, M., Parman, T., Green, C. E., Lewin, A. H., Ellis, W. Y., and Young, L. S., “Identification of (+)-Erythro-Mefloquine as an Active Enantiomer with Greater Efficacy than Mefloquine against Mycobacterium avium Infection in Mice.”, Antimicrobial agents and chemotherapy, vol. 56, no. 8, pp. 4202-6, 2012.

B. P. Dolan, Li, L., Veltri, C. A., Ireland, C. M., Bennink, J. R., and Yewdell, J. W., “Distinct pathways generate peptides from defective ribosomal products for CD8+ T cell immunosurveillance.”, J Immunol, vol. 186, no. 4, pp. 2065-72, 2011.

B. P. Dolan, Li, L., Veltri, C. A., Ireland, C. M., Bennink, J. R., and Yewdell, J. W., “Distinct pathways generate peptides from defective ribosomal products for CD8+ T cell immunosurveillance.”, Journal of immunology (Baltimore, Md. : 1950), vol. 186, no. 4, pp. 2065-72, 2011.

D. L. Swenson, Warfield, K. L., Warren, T. K., Lovejoy, C., Hassinger, J. N., Ruthel, G., Blouch, R. E., Moulton, H. M., Weller, D. D., Iversen, P. L., and Bavari, S., “Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection.”, Antimicrobial agents and chemotherapy, vol. 53, no. 5, pp. 2089-99, 2009.

H. Yin, Moulton, H. M., Betts, C., Seow, Y., Boutilier, J., Iverson, P. L., and Wood, M. J. A., “A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice.”, Human molecular genetics, vol. 18, no. 22, pp. 4405-14, 2009.

R. Abes, Arzumanov, A., Moulton, H. M., Abes, S., Ivanova, G., Gait, M. J., Iversen, P., and Lebleu, B., “Arginine-rich cell penetrating peptides: design, structure-activity, and applications to alter pre-mRNA splicing by steric-block oligonucleotides.”, Journal of peptide science : an official publication of the European Peptide Society, vol. 14, no. 4, pp. 455-60, 2008.

R. Abes, Arzumanov, A., Moulton, H. M., Abes, S., Ivanova, G., Gait, M. J., Iversen, P., and Lebleu, B., “Arginine-rich cell penetrating peptides: design, structure-activity, and applications to alter pre-mRNA splicing by steric-block oligonucleotides.”, Journal of peptide science : an official publication of the European Peptide Society, vol. 14, no. 4, pp. 455-60, 2008.

B. Lebleu, Moulton, H. M., Abes, R., Ivanova, G. D., Abes, S., Stein, D. A., Iversen, P. L., Arzumanov, A. A., and Gait, M. J., “Cell penetrating peptide conjugates of steric block oligonucleotides.”, Advanced drug delivery reviews, vol. 60, no. 4-5, pp. 517-29, 2008.

B. Lebleu, Moulton, H. M., Abes, R., Ivanova, G. D., Abes, S., Stein, D. A., Iversen, P. L., Arzumanov, A. A., and Gait, M. J., “Cell penetrating peptide conjugates of steric block oligonucleotides.”, Advanced drug delivery reviews, vol. 60, no. 4-5, pp. 517-29, 2008.

H. Yin, Moulton, H. M., Seow, Y., Boyd, C., Boutilier, J., Iverson, P., and Wood, M. J. A., “Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function.”, Human molecular genetics, vol. 17, no. 24, pp. 3909-18, 2008.

R. Abes, Moulton, H. M., Clair, P., Yang, S. - T., Abes, S., Melikov, K., Prevot, P., Youngblood, D. S., Iversen, P. L., Chernomordik, L. V., and Lebleu, B., “Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies.”, Nucleic acids research, vol. 36, no. 20, pp. 6343-54, 2008.

B. Wu, Moulton, H. M., Iversen, P. L., Jiang, J., Li, J., Li, J., Spurney, C. F., Sali, A., Guerron, A. D., Nagaraju, K., Doran, T., Lu, P., Xiao, X., and Lu, Q. Long, “Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer.”, Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 39, pp. 14814-9, 2008.

C. Lupfer, Stein, D. A., Mourich, D. V., Tepper, S. E., Iversen, P. L., and Pastey, M., “Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers.”, Archives of virology, vol. 153, no. 5, pp. 929-37, 2008.

J. E. Ishmael, Löhr, C. V., Fischer, K. A., and Kioussi, C., “Localization of myosin II regulatory light chain in the cerebral vasculature.”, Acta histochemica, vol. 110, no. 2, pp. 172-7, 2008.

N. Jearawiriyapaisarn, Moulton, H. M., Buckley, B., Roberts, J., Sazani, P., Fucharoen, S., Iversen, P. L., and Kole, R., “Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice.”, Molecular therapy : the journal of the American Society of Gene Therapy, vol. 16, no. 9, pp. 1624-9, 2008.

R. Burrer, Neuman, B. W., Ting, J. P. C., Stein, D. A., Moulton, H. M., Iversen, P. L., Kuhn, P., and Buchmeier, M. J., “Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models.”, Journal of virology, vol. 81, no. 11, pp. 5637-48, 2007.

N. B. Marshall, Oda, S. K., London, C. A., Moulton, H. M., Iversen, P. L., Kerkvliet, N. I., and Mourich, D. V., “Arginine-rich cell-penetrating peptides facilitate delivery of antisense oligomers into murine leukocytes and alter pre-mRNA splicing.”, Journal of immunological methods, vol. 325, no. 1-2, pp. 114-26, 2007.

H. M. Moulton, Fletcher, S., Neuman, B. W., McClorey, G., Stein, D. A., Abes, S., Wilton, S. D., Buchmeier, M. J., Lebleu, B., and Iversen, P. L., “Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo.”, Biochemical Society transactions, vol. 35, no. Pt 4, pp. 826-8, 2007.

R. P. Wu, Youngblood, D. S., Hassinger, J. N., Lovejoy, C. E., Nelson, M. H., Iversen, P. L., and Moulton, H. M., “Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity.”, Nucleic acids research, vol. 35, no. 15, pp. 5182-91, 2007.

R. Abes, Arzumanov, A. A., Moulton, H. M., Abes, S., Ivanova, G. D., Iversen, P. L., Gait, M. J., and Lebleu, B., “Cell-penetrating-peptide-based delivery of oligonucleotides: an overview.”, Biochemical Society transactions, vol. 35, no. Pt 4, pp. 775-9, 2007.

R. Abes, Arzumanov, A. A., Moulton, H. M., Abes, S., Ivanova, G. D., Iversen, P. L., Gait, M. J., and Lebleu, B., “Cell-penetrating-peptide-based delivery of oligonucleotides: an overview.”, Biochemical Society transactions, vol. 35, no. Pt 4, pp. 775-9, 2007.

C. Kioussi, Appu, M., Löhr, C. V., Fischer, K. A., Bajaj, G., Leid, M., and Ishmael, J. E., “Co-expression of myosin II regulatory light chain and the NMDAR1 subunit in neonatal and adult mouse brain.”, Brain research bulletin, vol. 74, no. 6, pp. 439-51, 2007.

L. E. Bermudez, Motamedi, N., Chee, C., Baimukanova, G., Kolonoski, P., Inderlied, C., Aralar, P., Wang, G., Phan, L. Tam, and Young, L. S., “EDP-420, a bicyclolide (bridged bicyclic macrolide), is active against Mycobacterium avium.”, Antimicrobial agents and chemotherapy, vol. 51, no. 5, pp. 1666-70, 2007.

Y. - J. Zhang, Wang, K. - Y., Stein, D. A., Patel, D., Watkins, R., Moulton, H. M., Iversen, P. L., and Matson, D. O., “Inhibition of replication and transcription activator and latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus by morpholino oligomers.”, Antiviral research, vol. 73, no. 1, pp. 12-23, 2007.

A. Kumar Indra, Castaneda, E., Antal, M. Cristina, Jiang, M., Messaddeq, N., Meng, X., Löhr, C. V., Gariglio, P., Kato, S., Wahli, W., Desvergne, B., Metzger, D., and Chambon, P., “Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes.”, The Journal of investigative dermatology, vol. 127, no. 5, pp. 1250-60, 2007.