Found 23 results
Author Title [ Type(Asc)] Year
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Journal Article
S. Abes, Moulton, H., Clair, P., Prevot, P., Youngblood, D. S., Wu, R. P., Iversen, P. L., and Lebleu, B., Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents., Journal of controlled release : official journal of the Controlled Release Society, vol. 116, no. 3, pp. 304-13, 2006.
N. Jearawiriyapaisarn, Moulton, H., Buckley, B., Roberts, J., Sazani, P., Fucharoen, S., Iversen, P. L., and Kole, R., Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice., Molecular therapy : the journal of the American Society of Gene Therapy, vol. 16, no. 9, pp. 1624-9, 2008.
D. S. Youngblood, Hatlevig, S. A., Hassinger, J. N., Iversen, P. L., and Moulton, H., Stability of cell-penetrating peptide-morpholino oligomer conjugates in human serum and in cells., Bioconjugate chemistry, vol. 18, no. 1, pp. 50-60, 2007.
A. Amantana, Moulton, H., Cate, M. L., Reddy, M. T., Whitehead, T., Hassinger, J. N., Youngblood, D. S., and Iversen, P. L., Pharmacokinetics, biodistribution, stability and toxicity of a cell-penetrating peptide-morpholino oligomer conjugate., Bioconjugate chemistry, vol. 18, no. 4, pp. 1325-31, 2007.
S. Fletcher, Honeyman, K., Fall, A. M., Harding, P. L., Johnsen, R. D., Steinhaus, J. P., Moulton, H., Iversen, P. L., and Wilton, S. D., Morpholino oligomer-mediated exon skipping averts the onset of dystrophic pathology in the mdx mouse., Molecular therapy : the journal of the American Society of Gene Therapy, vol. 15, no. 9, pp. 1587-92, 2007.
P. L. Iversen, Mourich, D. V., and Moulton, H., Monoclonal antibodies to two epitopes of beta-human chorionic gonadotropin for the treatment of cancer., Current opinion in molecular therapeutics, vol. 5, no. 2, pp. 156-60, 2003.
Y. - J. Zhang, Wang, K. - Y., Stein, D. A., Patel, D., Watkins, R., Moulton, H., Iversen, P. L., and Matson, D. O., Inhibition of replication and transcription activator and latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus by morpholino oligomers., Antiviral research, vol. 73, no. 1, pp. 12-23, 2007.
Q. Ge, Pastey, M., Kobasa, D., Puthavathana, P., Lupfer, C., Bestwick, R. K., Iversen, P. L., Chen, J., and Stein, D. A., Inhibition of multiple subtypes of influenza A virus in cell cultures with morpholino oligomers., Antimicrobial agents and chemotherapy, vol. 50, no. 11, pp. 3724-33, 2006.
C. Lupfer, Stein, D. A., Mourich, D. V., Tepper, S. E., Iversen, P. L., and Pastey, M., Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers., Archives of virology, vol. 153, no. 5, pp. 929-37, 2008.
J. Yuan, Stein, D. A., Lim, T., Qiu, D., Coughlin, S., Liu, Z., Wang, Y., Blouch, R., Moulton, H., Iversen, P. L., and Yang, D., Inhibition of coxsackievirus B3 in cell cultures and in mice by peptide-conjugated morpholino oligomers targeting the internal ribosome entry site., Journal of virology, vol. 80, no. 23, pp. 11510-9, 2006.
B. W. Neuman, Stein, D. A., Kroeker, A. D., Churchill, M. J., Kim, A. M., Kuhn, P., Dawson, P., Moulton, H., Bestwick, R. K., Iversen, P. L., and Buchmeier, M. J., Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers., Journal of virology, vol. 79, no. 15, pp. 9665-76, 2005.
B. W. Neuman, Stein, D. A., Kroeker, A. D., Moulton, H., Bestwick, R. K., Iversen, P. L., and Buchmeier, M. J., Inhibition and escape of SARS-CoV treated with antisense morpholino oligomers., Advances in experimental medicine and biology, vol. 581, pp. 567-71, 2006.
H. Moulton, Hase, M. C., Smith, K. M., and Iversen, P. L., HIV Tat peptide enhances cellular delivery of antisense morpholino oligomers., Antisense & nucleic acid drug development, vol. 13, no. 1, pp. 31-43, 2003.
B. Wu, Moulton, H., Iversen, P. L., Jiang, J., Li, J., Li, J., Spurney, C. F., Sali, A., Guerron, A. D., Nagaraju, K., Doran, T., Lu, P., Xiao, X., and Lu, Q. Long, Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer., Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 39, pp. 14814-9, 2008.
R. Abes, Moulton, H., Clair, P., Yang, S. - T., Abes, S., Melikov, K., Prevot, P., Youngblood, D. S., Iversen, P. L., Chernomordik, L. V., and Lebleu, B., Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies., Nucleic acids research, vol. 36, no. 20, pp. 6343-54, 2008.
D. L. Swenson, Warfield, K. L., Warren, T. K., Lovejoy, C., Hassinger, J. N., Ruthel, G., Blouch, R. E., Moulton, H., Weller, D. D., Iversen, P. L., and Bavari, S., Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection., Antimicrobial agents and chemotherapy, vol. 53, no. 5, pp. 2089-99, 2009.
H. Moulton, Nelson, M. H., Hatlevig, S. A., Reddy, M. T., and Iversen, P. L., Cellular uptake of antisense morpholino oligomers conjugated to arginine-rich peptides., Bioconjugate chemistry, vol. 15, no. 2, pp. 290-9, 2004.
R. P. Wu, Youngblood, D. S., Hassinger, J. N., Lovejoy, C. E., Nelson, M. H., Iversen, P. L., and Moulton, H., Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity., Nucleic acids research, vol. 35, no. 15, pp. 5182-91, 2007.
B. Lebleu, Moulton, H., Abes, R., Ivanova, G. D., Abes, S., Stein, D. A., Iversen, P. L., Arzumanov, A. A., and Gait, M. J., Cell penetrating peptide conjugates of steric block oligonucleotides., Advanced drug delivery reviews, vol. 60, no. 4-5, pp. 517-29, 2008.
M. H. Nelson, Stein, D. A., Kroeker, A. D., Hatlevig, S. A., Iversen, P. L., and Moulton, H., Arginine-rich peptide conjugation to morpholino oligomers: effects on antisense activity and specificity., Bioconjugate chemistry, vol. 16, no. 4, pp. 959-66, 2005.
R. Burrer, Neuman, B. W., Ting, J. P. C., Stein, D. A., Moulton, H., Iversen, P. L., Kuhn, P., and Buchmeier, M. J., Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models., Journal of virology, vol. 81, no. 11, pp. 5637-48, 2007.
B. W. Neuman, Stein, D. A., Kroeker, A. D., Paulino, A. D., Moulton, H., Iversen, P. L., and Buchmeier, M. J., Antisense morpholino-oligomers directed against the 5' end of the genome inhibit coronavirus proliferation and growth., Journal of virology, vol. 78, no. 11, pp. 5891-9, 2004.
H. Moulton, Yoshihara, P. H., Mason, D. H., Iversen, P. L., and Triozzi, P. L., Active specific immunotherapy with a beta-human chorionic gonadotropin peptide vaccine in patients with metastatic colorectal cancer: antibody response is associated with improved survival., Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 8, no. 7, pp. 2044-51, 2002.