Carlson College of Veterinary Medicine

B. Koscsó, Kurapati, S., Rodrigues, R. R., Nedjic, J., Gowda, K., Shin, C., Soni, C., Ashraf, A. Zaffran, Purushothaman, I., Palisoc, M., Xu, S., Sun, H., Chodisetti, S. Babu, Lin, E., Mack, M., Kawasawa, Y. Imamura, He, P., Rahman, Z. S. M., Aifantis, I., Shulzhenko, N., Morgun, A., and Bogunovic, M., “Gut-resident CX3CR1 macrophages induce tertiary lymphoid structures and IgA response in situ.”, Sci Immunol, vol. 5, no. 46, 2020.

S. S. Chiplunkar, Silva, C. A., Bermudez, L. E., and Danelishvili, L., “Characterization of membrane vesicles released by Mycobacterium avium in response to environment mimicking the macrophage phagosome.”, Future Microbiol, vol. 14, pp. 293-313, 2019.

V. R. Babaev, Ding, L., Zhang, Y., May, J. M., Ramsey, S. A., Vickers, K. C., and Linton, M. R. F., “Loss of 2 Akt (Protein Kinase B) Isoforms in Hematopoietic Cells Diminished Monocyte and Macrophage Survival and Reduces Atherosclerosis in Ldl Receptor-Null Mice.”, Arterioscler Thromb Vasc Biol, vol. 39, no. 2, pp. 156-169, 2019.

J. - Da Lin, Nishi, H., Poles, J., Niu, X., Mccauley, C., Rahman, K., Brown, E. J., Yeung, S. T., Vozhilla, N., Weinstock, A., Ramsey, S. A., Fisher, E. A., and Loke, P. 'ng, “Single-cell analysis of fate-mapped macrophages reveals heterogeneity, including stem-like properties, during atherosclerosis progression and regression.”, JCI Insight, vol. 4, no. 4, 2019.

L. Danelishvili, Rojony, R., Carson, K. L., Palmer, A. L., Rose, S. J., and Bermudez, L. E., “Mycobacterium avium subsp. hominissuis effector MAVA5_06970 promotes rapid apoptosis in secondary-infected macrophages during cell-to-cell spread.”, Virulence, vol. 9, no. 1, pp. 1287-1300, 2018.

P. S. Askovich, Ramsey, S. A., Diercks, A. H., Kennedy, K. A., Knijnenburg, T. A., and Aderem, A., “Identifying novel transcription factors involved in the inflammatory response by using binding site motif scanning in genomic regions defined by histone acetylation.”, PLoS One, vol. 12, no. 9, p. e0184850, 2017.

K. Rahman, Vengrenyuk, Y., Ramsey, S. A., Vila, N. Rotllan, Girgis, N. M., Liu, J., Gusarova, V., Gromada, J., Weinstock, A., Moore, K. J., Loke, P. 'ng, and Fisher, E. A., “Inflammatory Ly6Chi monocytes and their conversion to M2 macrophages drive atherosclerosis regression.”, J Clin Invest, vol. 127, no. 8, pp. 2904-2915, 2017.

L. Danelishvili, Chinison, J. J. J., Pham, T., Gupta, R., and Bermudez, L. E., “The Voltage-Dependent Anion Channels (VDAC) of Mycobacterium avium phagosome are associated with bacterial survival and lipid export in macrophages.”, Sci Rep, vol. 7, no. 1, p. 7007, 2017.

J. J. Chinison, Danelishvili, L., Gupta, R., Rose, S. J., Babrak, L. M., and Bermudez, L. E., “Identification of Mycobacterium avium subsp. hominissuis secreted proteins using an in vitro system mimicking the phagosomal environment.”, BMC Microbiol, vol. 16, no. 1, p. 270, 2016.

L. E. Bermudez, Danelishvili, L., Babrack, L., and Pham, T., “Evidence for genes associated with the ability of Mycobacterium avium subsp. hominissuis to escape apoptotic macrophages.”, Front Cell Infect Microbiol, vol. 5, p. 63, 2015.

M. A. Gillespie, Gold, E. S., Ramsey, S. A., Podolsky, I., Aderem, A., and Ranish, J. A., “An LXR-NCOA5 gene regulatory complex directs inflammatory crosstalk-dependent repression of macrophage cholesterol efflux.”, EMBO J, vol. 34, no. 9, pp. 1244-58, 2015.

L. Danelishvili and Bermudez, L. E., “Mycobacterium avium MAV_2941 mimics phosphoinositol-3-kinase to interfere with macrophage phagosome maturation.”, Microbes Infect, vol. 17, no. 9, pp. 628-37, 2015.

S. A. Ramsey, Vengrenyuk, Y., Menon, P., Podolsky, I., Feig, J. E., Aderem, A., Fisher, E. A., and Gold, E. S., “Epigenome-guided analysis of the transcriptome of plaque macrophages during atherosclerosis regression reveals activation of the Wnt signaling pathway.”, PLoS Genet, vol. 10, no. 12, p. e1004828, 2014.

N. Motamedi, Danelishvili, L., and Bermudez, L. E., “Identification of Mycobacterium avium genes associated with resistance to host antimicrobial peptides.”, J Med Microbiol, vol. 63, no. Pt 7, pp. 923-930, 2014.

L. Danelishvili, Stang, B., and Bermudez, L. E., “Identification of Mycobacterium avium genes expressed during in vivo infection and the role of the oligopeptide transporter OppA in virulence.”, Microb Pathog, vol. 76, pp. 67-76, 2014.

L. Danelishvili, Babrak, L., Rose, S. J., Everman, J., and Bermudez, L. E., “Mycobacterium tuberculosis alters the metalloprotease activity of the COP9 signalosome.”, mBio, vol. 5, no. 4, 2014.

L. Danelishvili and Bermudez, L. E., “Analysis of pyroptosis in bacterial infection.”, Methods Mol Biol, vol. 1004, pp. 67-73, 2013.

J. Meznarich, Malchodi, L., Helterline, D., Ramsey, S. A., Bertko, K., Plummer, T., Plawman, A., Gold, E., and Stempien-Otero, A., “Urokinase plasminogen activator induces pro-fibrotic/m2 phenotype in murine cardiac macrophages.”, PLoS One, vol. 8, no. 3, p. e57837, 2013.

G. Chen, Severo, M. S., Sakhon, O. S., Choy, A., Herron, M. J., Felsheim, R. F., Wiryawan, H., Liao, J., Johns, J. L., Munderloh, U. G., Sutterwala, F. S., Kotsyfakis, M., and Pedra, J. H. F., “Anaplasma phagocytophilum dihydrolipoamide dehydrogenase 1 affects host-derived immunopathology during microbial colonization.”, Infect Immun, vol. 80, no. 9, pp. 3194-205, 2012.

E. S. Gold, Ramsey, S. A., Sartain, M. J., Selinummi, J., Podolsky, I., Rodriguez, D. J., Moritz, R. L., and Aderem, A., “ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol-induced lipid body formation.”, J Exp Med, vol. 209, no. 4, pp. 807-17, 2012.

S. D. Farris, Hu, J. Hong, Krishnan, R., Emery, I., Chu, T., Du, L., Kremen, M., Dichek, H. L., Gold, E., Ramsey, S. A., and Dichek, D. A., “Mechanisms of urokinase plasminogen activator (uPA)-mediated atherosclerosis: role of the uPA receptor and S100A8/A9 proteins.”, J Biol Chem, vol. 286, no. 25, pp. 22665-77, 2011.

N. Luckschander, Hall, J. A., Gaschen, F., Forster, U., Wenzlow, N., Hermann, P., Allenspach, K., Dobbelaere, D., Burgener, I. A., and Welle, M., “Activation of nuclear factor-kappaB in dogs with chronic enteropathies.”, Vet Immunol Immunopathol, vol. 133, no. 2-4, pp. 228-36, 2010.

Y. -jun Li, Danelishvili, L., Wagner, D., Petrofsky, M., and Bermudez, L. E., “Identification of virulence determinants of Mycobacterium avium that impact on the ability to resist host killing mechanisms.”, J Med Microbiol, vol. 59, no. Pt 1, pp. 8-16, 2010.

L. Danelishvili, Yamazaki, Y., Selker, J., and Bermudez, L. E., “Secreted Mycobacterium tuberculosis Rv3654c and Rv3655c proteins participate in the suppression of macrophage apoptosis.”, PLoS One, vol. 5, no. 5, p. e10474, 2010.

V. Litvak, Ramsey, S. A., Rust, A. G., Zak, D. E., Kennedy, K. A., Lampano, A. E., Nykter, M., Shmulevich, I., and Aderem, A., “Function of C/EBPdelta in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals.”, Nat Immunol, vol. 10, no. 4, pp. 437-43, 2009.