Carlson College of Veterinary Medicine

H. Yin, Boisguerin, P., Moulton, H. M., Betts, C., Seow, Y., Boutilier, J., Wang, Q., Walsh, A., Lebleu, B., and Wood, M. Ja, “Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency.”, Mol Ther Nucleic Acids, vol. 2, p. e124, 2013.

H. M. Moulton, “In vivo delivery of morpholino oligos by cell-penetrating peptides.”, Current pharmaceutical design, vol. 19, no. 16, pp. 2963-9, 2013.

H. M. Moulton, “In vivo delivery of morpholino oligos by cell-penetrating peptides.”, Curr Pharm Des, vol. 19, no. 16, pp. 2963-9, 2013.

H. M. Moulton, “Cell-penetrating peptides enhance systemic delivery of antisense morpholino oligomers.”, Methods in molecular biology (Clifton, N.J.), vol. 867, pp. 407-14, 2012.

B. Wu, Lu, P., Cloer, C., Shaban, M., Grewal, S., Milazi, S., Shah, S. N., Moulton, H. M., and Lu, Q. Long, “Long-term rescue of dystrophin expression and improvement in muscle pathology and function in dystrophic mdx mice by peptide-conjugated morpholino.”, The American journal of pathology, vol. 181, no. 2, pp. 392-400, 2012.

B. Wu, Lu, P., Cloer, C., Shaban, M., Grewal, S., Milazi, S., Shah, S. N., Moulton, H. M., and Lu, Q. Long, “Long-term rescue of dystrophin expression and improvement in muscle pathology and function in dystrophic mdx mice by peptide-conjugated morpholino.”, Am J Pathol, vol. 181, no. 2, pp. 392-400, 2012.

H. Yin, Moulton, H. M., Betts, C., and Wood, M., “CPP-directed oligonucleotide exon skipping in animal models of Duchenne muscular dystrophy.”, Methods in molecular biology (Clifton, N.J.), vol. 683, pp. 321-38, 2011.

H. Yin, Moulton, H. M., Betts, C., and Wood, M., “CPP-directed oligonucleotide exon skipping in animal models of Duchenne muscular dystrophy.”, Methods Mol Biol, vol. 683, pp. 321-38, 2011.

B. W. Neuman, Bederka, L. H., Stein, D. A., Ting, J. P. C., Moulton, H. M., and Buchmeier, M. J., “Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors.”, Antimicrob Agents Chemother, vol. 55, no. 10, pp. 4631-8, 2011.

B. W. Neuman, Bederka, L. H., Stein, D. A., Ting, J. P. C., Moulton, H. M., and Buchmeier, M. J., “Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors.”, Antimicrobial agents and chemotherapy, vol. 55, no. 10, pp. 4631-8, 2011.

A. Crisp, Yin, H., Goyenvalle, A., Betts, C., Moulton, H. M., Seow, Y., Babbs, A., Merritt, T., Saleh, A. F., Gait, M. J., Stuckey, D. J., Clarke, K., Davies, K. E., and Wood, M. J. A., “Diaphragm rescue alone prevents heart dysfunction in dystrophic mice.”, Human molecular genetics, vol. 20, no. 3, pp. 413-21, 2011.

A. Crisp, Yin, H., Goyenvalle, A., Betts, C., Moulton, H. M., Seow, Y., Babbs, A., Merritt, T., Saleh, A. F., Gait, M. J., Stuckey, D. J., Clarke, K., Davies, K. E., and Wood, M. J. A., “Diaphragm rescue alone prevents heart dysfunction in dystrophic mice.”, Hum Mol Genet, vol. 20, no. 3, pp. 413-21, 2011.

S. Fletcher, Adams, A. M., Johnsen, R. D., Greer, K., Moulton, H. M., and Wilton, S. D., “Dystrophin isoform induction in vivo by antisense-mediated alternative splicing.”, Mol Ther, vol. 18, no. 6, pp. 1218-23, 2010.

S. Fletcher, Adams, A. M., Johnsen, R. D., Greer, K., Moulton, H. M., and Wilton, S. D., “Dystrophin isoform induction in vivo by antisense-mediated alternative splicing.”, Molecular therapy : the journal of the American Society of Gene Therapy, vol. 18, no. 6, pp. 1218-23, 2010.

H. Yin, Moulton, H. M., Betts, C., Merritt, T., Seow, Y., Ashraf, S., Wang, Q., Boutilier, J., and Wood, M. Ja, “Functional rescue of dystrophin-deficient mdx mice by a chimeric peptide-PMO.”, Mol Ther, vol. 18, no. 10, pp. 1822-9, 2010.

H. Yin, Moulton, H. M., Betts, C., Merritt, T., Seow, Y., Ashraf, S., Wang, Q., Boutilier, J., and Wood, M. J. A., “Functional rescue of dystrophin-deficient mdx mice by a chimeric peptide-PMO.”, Molecular therapy : the journal of the American Society of Gene Therapy, vol. 18, no. 10, pp. 1822-9, 2010.

Q. Wang, Yin, H., Camelliti, P., Betts, C., Moulton, H. M., Lee, H., Saleh, A. F., Gait, M. J., and Wood, M. J. A., “In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping activity for Duchenne muscular dystrophy.”, The journal of gene medicine, vol. 12, no. 4, pp. 354-64, 2010.

Q. Wang, Yin, H., Camelliti, P., Betts, C., Moulton, H. M., Lee, H., Saleh, A. F., Gait, M. J., and Wood, M. J. A., “In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping activity for Duchenne muscular dystrophy.”, J Gene Med, vol. 12, no. 4, pp. 354-64, 2010.

N. Jearawiriyapaisarn, Moulton, H. M., Sazani, P., Kole, R., and Willis, M. S., “Long-term improvement in mdx cardiomyopathy after therapy with peptide-conjugated morpholino oligomers.”, Cardiovascular research, vol. 85, no. 3, pp. 444-53, 2010.

N. Jearawiriyapaisarn, Moulton, H. M., Sazani, P., Kole, R., and Willis, M. S., “Long-term improvement in mdx cardiomyopathy after therapy with peptide-conjugated morpholino oligomers.”, Cardiovasc Res, vol. 85, no. 3, pp. 444-53, 2010.

H. M. Moulton and Moulton, J. D., “Morpholinos and their peptide conjugates: therapeutic promise and challenge for Duchenne muscular dystrophy.”, Biochim Biophys Acta, vol. 1798, no. 12, pp. 2296-303, 2010.

H. M. Moulton and Moulton, J. D., “Morpholinos and their peptide conjugates: therapeutic promise and challenge for Duchenne muscular dystrophy.”, Biochimica et biophysica acta, vol. 1798, no. 12, pp. 2296-303, 2010.

D. L. Swenson, Warfield, K. L., Warren, T. K., Lovejoy, C., Hassinger, J. N., Ruthel, G., Blouch, R. E., Moulton, H. M., Weller, D. D., Iversen, P. L., and Bavari, S., “Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection.”, Antimicrobial agents and chemotherapy, vol. 53, no. 5, pp. 2089-99, 2009.

H. Yin, Moulton, H. M., Betts, C., Seow, Y., Boutilier, J., Iverson, P. L., and Wood, M. J. A., “A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice.”, Human molecular genetics, vol. 18, no. 22, pp. 4405-14, 2009.

H. M. Moulton, Wu, B., Jearawiriyapaisarn, N., Sazani, P., Lu, Q. Long, and Kole, R., “Peptide-morpholino conjugate: a promising therapeutic for Duchenne muscular dystrophy.”, Annals of the New York Academy of Sciences, vol. 1175, pp. 55-60, 2009.