Found 55 results
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Journal Article
J. L. Sanders, Zhou, Y., Moulton, H. M., Moulton, Z. X., McLeod, R., Dubey, J. P., Weiss, L. M., and Kent, M. L., The zebrafish, Danio rerio, as a model for Toxoplasma gondii: an initial description of infection in fish., Journal of fish diseases, vol. 38, no. 7, pp. 675-9, 2015.
S. Abes, Moulton, H. M., Clair, P., Prevot, P., Youngblood, D. S., Wu, R. P., Iversen, P. L., and Lebleu, B., Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents., Journal of controlled release : official journal of the Controlled Release Society, vol. 116, no. 3, pp. 304-13, 2006.
R. Rajsbaum, Versteeg, G. A., Schmid, S., Maestre, A. M., Belicha-Villanueva, A., Martínez-Romero, C., Patel, J. R., Morrison, J., Pisanelli, G., Miorin, L., Laurent-Rolle, M., Moulton, H. M., Stein, D. A., Fernandez-Sesma, A., tenOever, B. R., and García-Sastre, A., Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response., Immunity, vol. 40, no. 6, pp. 880-95, 2014.
N. Jearawiriyapaisarn, Moulton, H. M., Buckley, B., Roberts, J., Sazani, P., Fucharoen, S., Iversen, P. L., and Kole, R., Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice., Molecular therapy : the journal of the American Society of Gene Therapy, vol. 16, no. 9, pp. 1624-9, 2008.
D. S. Youngblood, Hatlevig, S. A., Hassinger, J. N., Iversen, P. L., and Moulton, H. M., Stability of cell-penetrating peptide-morpholino oligomer conjugates in human serum and in cells., Bioconjugate chemistry, vol. 18, no. 1, pp. 50-60, 2007.
S. Svasti, Suwanmanee, T., Fucharoen, S., Moulton, H. M., Nelson, M. H., Maeda, N., Smithies, O., and Kole, R., RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice., Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 4, pp. 1205-10, 2009.
A. Amantana, Moulton, H. M., Cate, M. L., Reddy, M. T., Whitehead, T., Hassinger, J. N., Youngblood, D. S., and Iversen, P. L., Pharmacokinetics, biodistribution, stability and toxicity of a cell-penetrating peptide-morpholino oligomer conjugate., Bioconjugate chemistry, vol. 18, no. 4, pp. 1325-31, 2007.
H. M. Moulton, Wu, B., Jearawiriyapaisarn, N., Sazani, P., Lu, Q. Long, and Kole, R., Peptide-morpholino conjugate: a promising therapeutic for Duchenne muscular dystrophy., Annals of the New York Academy of Sciences, vol. 1175, pp. 55-60, 2009.
S. Abes, Moulton, H. M., Turner, J., Clair, P., Richard, J. P., Iversen, P., Gait, M. J., and Lebleu, B., Peptide-based delivery of nucleic acids: design, mechanism of uptake and applications to splice-correcting oligonucleotides., Biochemical Society transactions, vol. 35, no. Pt 1, pp. 53-5, 2007.
H. M. Moulton and Moulton, J. D., Peptide-assisted delivery of steric-blocking antisense oligomers., Current opinion in molecular therapeutics, vol. 5, no. 2, pp. 123-32, 2003.
H. M. Moulton and Moulton, J. D., Morpholinos and their peptide conjugates: therapeutic promise and challenge for Duchenne muscular dystrophy., Biochimica et biophysica acta, vol. 1798, no. 12, pp. 2296-303, 2010.
S. Fletcher, Honeyman, K., Fall, A. M., Harding, P. L., Johnsen, R. D., Steinhaus, J. P., Moulton, H. M., Iversen, P. L., and Wilton, S. D., Morpholino oligomer-mediated exon skipping averts the onset of dystrophic pathology in the mdx mouse., Molecular therapy : the journal of the American Society of Gene Therapy, vol. 15, no. 9, pp. 1587-92, 2007.
P. L. Iversen, Mourich, D. V., and Moulton, H. M., Monoclonal antibodies to two epitopes of beta-human chorionic gonadotropin for the treatment of cancer., Current opinion in molecular therapeutics, vol. 5, no. 2, pp. 156-60, 2003.
B. Wu, Lu, P., Cloer, C., Shaban, M., Grewal, S., Milazi, S., Shah, S. N., Moulton, H. M., and Lu, Q. Long, Long-term rescue of dystrophin expression and improvement in muscle pathology and function in dystrophic mdx mice by peptide-conjugated morpholino., The American journal of pathology, vol. 181, no. 2, pp. 392-400, 2012.
N. Jearawiriyapaisarn, Moulton, H. M., Sazani, P., Kole, R., and Willis, M. S., Long-term improvement in mdx cardiomyopathy after therapy with peptide-conjugated morpholino oligomers., Cardiovascular research, vol. 85, no. 3, pp. 444-53, 2010.
Y. - J. Zhang, Wang, K. - Y., Stein, D. A., Patel, D., Watkins, R., Moulton, H. M., Iversen, P. L., and Matson, D. O., Inhibition of replication and transcription activator and latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus by morpholino oligomers., Antiviral research, vol. 73, no. 1, pp. 12-23, 2007.
M. Alonso, Stein, D. A., Thomann, E., Moulton, H. M., Leong, J. C., Iversen, P., and Mourich, D. V., Inhibition of infectious haematopoietic necrosis virus in cell cultures with peptide-conjugated morpholino oligomers., Journal of fish diseases, vol. 28, no. 7, pp. 399-410, 2005.
B. L. Geller, Deere, J. D., Stein, D. A., Kroeker, A. D., Moulton, H. M., and Iversen, P. L., Inhibition of gene expression in Escherichia coli by antisense phosphorodiamidate morpholino oligomers., Antimicrobial agents and chemotherapy, vol. 47, no. 10, pp. 3233-9, 2003.
T. S. Deas, Binduga-Gajewska, I., Tilgner, M., Ren, P., Stein, D. A., Moulton, H. M., Iversen, P. L., Kauffman, E. B., Kramer, L. D., and Shi, P. Y., Inhibition of flavivirus infections by antisense oligomers specifically suppressing viral translation and RNA replication., J Virol, vol. 79, no. 8, pp. 4599-609, 2005.
J. Yuan, Stein, D. A., Lim, T., Qiu, D., Coughlin, S., Liu, Z., Wang, Y., Blouch, R., Moulton, H. M., Iversen, P. L., and Yang, D., Inhibition of coxsackievirus B3 in cell cultures and in mice by peptide-conjugated morpholino oligomers targeting the internal ribosome entry site., Journal of virology, vol. 80, no. 23, pp. 11510-9, 2006.
B. W. Neuman, Stein, D. A., Kroeker, A. D., Churchill, M. J., Kim, A. M., Kuhn, P., Dawson, P., Moulton, H. M., Bestwick, R. K., Iversen, P. L., and Buchmeier, M. J., Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers., Journal of virology, vol. 79, no. 15, pp. 9665-76, 2005.
B. W. Neuman, Stein, D. A., Kroeker, A. D., Moulton, H. M., Bestwick, R. K., Iversen, P. L., and Buchmeier, M. J., Inhibition and escape of SARS-CoV treated with antisense morpholino oligomers., Advances in experimental medicine and biology, vol. 581, pp. 567-71, 2006.
G. McClorey, Fall, A. M., Moulton, H. M., Iversen, P. L., Rasko, J. E., Ryan, M., Fletcher, S., and Wilton, S. D., Induced dystrophin exon skipping in human muscle explants., Neuromuscular disorders : NMD, vol. 16, no. 9-10, pp. 583-90, 2006.
H. M. Moulton, In vivo delivery of morpholino oligos by cell-penetrating peptides., Current pharmaceutical design, vol. 19, no. 16, pp. 2963-9, 2013.
Q. Wang, Yin, H., Camelliti, P., Betts, C., Moulton, H. M., Lee, H., Saleh, A. F., Gait, M. J., and Wood, M. J. A., In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping activity for Duchenne muscular dystrophy., The journal of gene medicine, vol. 12, no. 4, pp. 354-64, 2010.

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