Carlson College of Veterinary Medicine

S. D. Farris, Hu, J. Hong, Krishnan, R., Emery, I., Chu, T., Du, L., Kremen, M., Dichek, H. L., Gold, E., Ramsey, S. A., and Dichek, D. A., “Mechanisms of urokinase plasminogen activator (uPA)-mediated atherosclerosis: role of the uPA receptor and S100A8/A9 proteins.”, J Biol Chem, vol. 286, no. 25, pp. 22665-77, 2011.

E. Fu, Ramsey, S. A., Kauffman, P., Lutz, B., and Yager, P., “Transport in two-dimensional paper networks.”, Microfluid Nanofluidics, vol. 10, no. 1, pp. 29-35, 2011.

A. V. Ratushny, Saleem, R. A., Sitko, K., Ramsey, S. A., and Aitchison, J. D., “Asymmetric positive feedback loops reliably control biological responses.”, Mol Syst Biol, vol. 8, p. 577, 2012.

E. S. Gold, Ramsey, S. A., Sartain, M. J., Selinummi, J., Podolsky, I., Rodriguez, D. J., Moritz, R. L., and Aderem, A., “ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol-induced lipid body formation.”, J Exp Med, vol. 209, no. 4, pp. 807-17, 2012.

J. Meznarich, Malchodi, L., Helterline, D., Ramsey, S. A., Bertko, K., Plummer, T., Plawman, A., Gold, E., and Stempien-Otero, A., “Urokinase plasminogen activator induces pro-fibrotic/m2 phenotype in murine cardiac macrophages.”, PLoS One, vol. 8, no. 3, p. e57837, 2013.

S. A. Ramsey, Vengrenyuk, Y., Menon, P., Podolsky, I., Feig, J. E., Aderem, A., Fisher, E. A., and Gold, E. S., “Epigenome-guided analysis of the transcriptome of plaque macrophages during atherosclerosis regression reveals activation of the Wnt signaling pathway.”, PLoS Genet, vol. 10, no. 12, p. e1004828, 2014.

T. A. Knijnenburg, Ramsey, S. A., Berman, B. P., Kennedy, K. A., Smit, A. F. A., Wessels, L. F. A., Laird, P. W., Aderem, A., and Shmulevich, I., “Multiscale representation of genomic signals.”, Nat Methods, vol. 11, no. 6, pp. 689-94, 2014.

Y. Vengrenyuk, Nishi, H., Long, X., Ouimet, M., Savji, N., Martinez, F. O., Cassella, C. P., Moore, K. J., Ramsey, S. A., Miano, J. M., and Fisher, E. A., “Cholesterol loading reprograms the microRNA-143/145-myocardin axis to convert aortic smooth muscle cells to a dysfunctional macrophage-like phenotype.”, Arterioscler Thromb Vasc Biol, vol. 35, no. 3, pp. 535-46, 2015.

J. Yang and Ramsey, S. A., “A DNA shape-based regulatory score improves position-weight matrix-based recognition of transcription factor binding sites.”, Bioinformatics, vol. 31, no. 21, pp. 3445-50, 2015.

S. A. Ramsey, “An Empirical Prior Improves Accuracy for Bayesian Estimation of Transcription Factor Binding Site Frequencies within Gene Promoters.”, Bioinform Biol Insights, vol. 9, no. Suppl 4, pp. 59-69, 2015.

M. A. Gillespie, Gold, E. S., Ramsey, S. A., Podolsky, I., Aderem, A., and Ranish, J. A., “An LXR-NCOA5 gene regulatory complex directs inflammatory crosstalk-dependent repression of macrophage cholesterol efflux.”, EMBO J, vol. 34, no. 9, pp. 1244-58, 2015.

X. Dong, Yambartsev, A., Ramsey, S. A., Thomas, L. D., Shulzhenko, N., and Morgun, A., “Reverse enGENEering of Regulatory Networks from Big Data: A Roadmap for Biologists.”, Bioinformatics and biology insights, vol. 9, pp. 61-74, 2015.

X. Dong, Yambartsev, A., Ramsey, S. A., Thomas, L. D., Shulzhenko, N., and Morgun, A., “Reverse enGENEering of Regulatory Networks from Big Data: A Roadmap for Biologists.”, Bioinform Biol Insights, vol. 9, pp. 61-74, 2015.

M. Choudhury and Ramsey, S. A., “Identifying Cell Type-Specific Transcription Factors by Integrating ChIP-seq and eQTL Data-Application to Monocyte Gene Regulation.”, Gene Regul Syst Bio, vol. 10, pp. 105-110, 2016.

T. Liang, Robinson, R., Houghtaling, J., Fridley, G., Ramsey, S. A., and Fu, E., “Investigation of Reagent Delivery Formats in a Multivalent Malaria Sandwich Immunoassay and Implications for Assay Performance.”, Anal Chem, vol. 88, no. 4, pp. 2311-20, 2016.

S. A. Ramsey, Xu, T., Goodall, C., Rhodes, A. C., Kashyap, A., He, J., and Bracha, S., “Cross-species analysis of the canine and human bladder cancer transcriptome and exome.”, Genes Chromosomes Cancer, vol. 56, no. 4, pp. 328-343, 2017.

P. S. Askovich, Ramsey, S. A., Diercks, A. H., Kennedy, K. A., Knijnenburg, T. A., and Aderem, A., “Identifying novel transcription factors involved in the inflammatory response by using binding site motif scanning in genomic regions defined by histone acetylation.”, PLoS One, vol. 12, no. 9, p. e0184850, 2017.

K. Rahman, Vengrenyuk, Y., Ramsey, S. A., Vila, N. Rotllan, Girgis, N. M., Liu, J., Gusarova, V., Gromada, J., Weinstock, A., Moore, K. J., Loke, P. 'ng, and Fisher, E. A., “Inflammatory Ly6Chi monocytes and their conversion to M2 macrophages drive atherosclerosis regression.”, J Clin Invest, vol. 127, no. 8, pp. 2904-2915, 2017.

A. Z. Yu and Ramsey, S. A., “A Computational Systems Biology Approach for Identifying Candidate Drugs for Repositioning for Cardiovascular Disease.”, Interdiscip Sci, vol. 10, no. 2, pp. 449-454, 2018.

A. J. Singh, Ramsey, S. A., Filtz, T. M., and Kioussi, C., “Differential gene regulatory networks in development and disease.”, Cell Mol Life Sci, vol. 75, no. 6, pp. 1013-1025, 2018.

A. J. Singh, Chang, C. - N., Ma, H. - Y., Ramsey, S. A., Filtz, T. M., and Kioussi, C., “FACS-Seq analysis of Pax3-derived cells identifies non-myogenic lineages in the embryonic forelimb.”, Sci Rep, vol. 8, no. 1, p. 7670, 2018.

S. A. Ramsey, “A Method for Cross-Species Visualization and Analysis of RNA-Sequence Data.”, Methods Mol Biol, vol. 1702, pp. 291-305, 2018.

J. V. Brady, Troyer, R. M., Ramsey, S. A., Leeper, H., Yang, L., Maier, C. S., Goodall, C. P., Ruby, C. E., Albarqi, H. A. M., Taratula, O., and Bracha, S., “A Preliminary Proteomic Investigation of Circulating Exosomes and Discovery of Biomarkers Associated with the Progression of Osteosarcoma in a Clinical Model of Spontaneous Disease.”, Transl Oncol, vol. 11, no. 5, pp. 1137-1146, 2018.

H. R. C. Shoen, Rose, S. J., Ramsey, S. A., de Morais, H. Autran, and Bermudez, L. E., “Analysis of Staphylococcus infections in a veterinary teaching hospital from 2012 to 2015.”, Comp Immunol Microbiol Infect Dis, vol. 66, p. 101332, 2019.

“The Biomedical Data Translator Program: Conception, Culture, and Community.”, Clin Transl Sci, vol. 12, no. 2, pp. 91-94, 2019.