The Shulzenko lab is interested in understanding how cells of the immune system communicate with other host systems and the resident microorganisms (microbiota) in complex organisms in health and disease. This co-existence is beneficial for both sides but has to be tightly regulated in order to prevent disease development. In order to disclose the mechanisms of these physiological and associated pathological processes, the lab uses a systems approach and analyzes host and microbiota simultaneously. This is done through host transcriptome profiling and global microbiome analysis by next generation sequencing to identify the key regulators of the process. These findings are further validated by directed perturbations of host and microbiota using gnotobiotic mice, i.e. those colonized with defined microbiota. Lab’s recent work in chronic enteropathy of immunodeficient hosts (human and mouse) and in type 2 diabetes focuses on finding microbiota members that can be harmful or beneficial for these diseases.
Morgun & Shulzhenko Labs
2002: Ph. D. Degree, Federal University of Sao Paulo - Escola Paulista de Medicina, São Paulo, SP, Brazil.
1995: M.D. Diploma with honors, Kharkiv Medical University, Kharkiv, Ukraine.
2018-Present: Associate Professor, Carlson College of Veterinary Medicine, Oregon State University, Corvallis, OR
2012-2018: Assistant Professor, Carlson College of Veterinary Medicine, Oregon State University, Corvallis, OR
2011-2012: Research Assistant Professor, College of Pharmacy, Oregon State University, Corvallis, OR
2005-2011: Postdoctoral Fellow, T Cell Tolerance and Memory Section, Laboratory of Cellular and Molecular Immunology (LCMI), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA
2001-2005: Staff Scientist/Supervisor of Molecular Biology Section, Immunogenetics Division, Association of the Incentive Fund for Psycho-pharmacology (AFIP), Federal University of Sao Paulo, São Paulo, Brazil.